Gumapang Ka sa Lusak revolves around the lives of engaged sweethearts Rachel (Jennylyn Mercado), an aspiring young actress, and Levi (Dennis Trillo), a poor, happy-go-lucky guy.

In the town of San Felipe, Rachel's beauty stands out. She becomes the object of desire for many men, including their own mayor, Edmundo Guatlo (Al Tantay). With a fervent desire to have her, Mayor Guatlo will use all his power to make Rachel his mistress. Rachel rejects all the gifts and favors offered by the mayor. However, she will fall into the wicked mayor's trap after a series of misfortunes happen to her loved ones, including her fiancé Levi, who gets imprisoned due to an illegal activity.

Although the mayor's wife, Rowena (Sandy Andolong), is aware of her husband's infidelity, she goes along with it as long as the affair doesn't affect her comfortable and powerful position in the society.

However, things will make a sudden turn when Mayor Guatlo's secret is exposed to the public. It is a secret that will uncover a series of other secrets.

Will the mayor be able to win when he runs anew for the mayoralty post in the coming election? Will the expose free Rachel from being the Mayor's mistress? Will fate lead her back to the loving arms of Levi? Or is it too late for the hapless lovers to rekindle their affection?

Completing the cast of Gumapang Ka sa Lusak are Lotlot de Leon, Julio Diaz, Glydel Mercado, Ronnie Lazaro, Luz Valdez, Michael Sandico and Patricia Ysmael; together with the Kapuso network's homegrown stars: Mart Escudero, Ryza Cenon, Vaness del Moral, Prince Stefan and Shaun Rodriguez.

Follow the stories of love and ambition in Sine Novela presents Gumapang Ka sa Lusak, weekdays after Daisy Siete, part of GMA-7's Dramarama sa Hapon programming block.